>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------------------------------------------
---------MNGTE--GDNFYVP----FSNKTGLARSPYEYPQY-YLAEPWK--------
-YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVT
MYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGN
THAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESY
VVYMFVVHFLVPFVIIFFCYGRLLCTV---------------------------------
------------------------------------------------------------
------------------------------KEAAAAQQ----------ESASTQKA----
-------------------------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGS
D---FGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCCGKN------PLGDDE
--SGASTSKTEVSSVS-TSPVSPA------------------------------------
---------------------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------------------------------------------
---------MNGTE--GPNFYVP----FSNITGVVRSPFEQPQY-YLAEPWQ--------
-FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTT
LYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGE
NHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESF
VIYMFVVHFTIPMIVIFFCYGQLVFTV---------------------------------
------------------------------------------------------------
------------------------------KEAAAQQQ----------ESATTQKA----
-------------------------EKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGS
N---FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCCGKN------PLGDDE
--ASATASKTE------TSQVAPA------------------------------------
---------------------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------------------------------------------
---------MNGTE--GINFYVP----MSNKTGVVRSPFEYPQY-YLAEPWK--------
-YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVT
FYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSA
THAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESY
VLYMFVIHFIIPVVVIFFSYGRLICKV---------------------------------
------------------------------------------------------------
------------------------------REAAAQQQ----------ESATTQKA----
-------------------------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGA
D---FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICCGKN------PFGDED
VSSTVSQSKTEVSSVS-SSQVSPA------------------------------------
---------------------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------------------------------------------
---------MNGTE--GKNFYVP----MSNRTGLVRSPFEYPQY-YLAEPWQ--------
-FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVT
FYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSS
SHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESY
VIYMFVCHFILPVAVIFFTYGRLVCTV---------------------------------
------------------------------------------------------------
------------------------------KAAAAQQQ----------DSASTQKA----
-------------------------EREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGA
D---FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFCGKN------PLGDDE
-SSTVSTSKTEVSS------VSPA------------------------------------
---------------------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------------------------------------------
---------MNGTE--GNNFYVP----LSNRTGLVRSPFEYPQY-YLAEPWQ--------
-FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVT
FYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSS
THASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESY
VLYMFICHFILPVTIIFFTYGRLVCTV---------------------------------
------------------------------------------------------------
------------------------------KAAAAQQQ----------DSASTQKA----
-------------------------EREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGA
A---FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFCGKN------PLGDEE
-SSTVSTSKTEVSS------VSPA------------------------------------
---------------------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------------------------------------------
---------MKQVPEFHEDFYIPIPLDINNLS--AYSPFLVPQD-HLGNQGI--------
-FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLS
FYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKT
PHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESY
VMFLFCFCFAVPFGTIVFCYGQLLITL---------------------------------
------------------------------------------------------------
------------------------------KLAAKAQA----------DSASTQKA----
-------------------------EREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGE
E---FDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVCGKN-------IEEDE
--ASTSSQVTQVSS------VAPEK-----------------------------------
---------------------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
---------MRKMS--EEEFYL-----FKNISSV--GPWDGPQY-HIAPVWA--------
-FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPV
FVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSS
KHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESY
TWFLFIFCFIVPLSLICFSYTQLLRAL---------------------------------
------------------------------------------------------------
------------------------------KAVAAQQQ----------ESATTQKA----
-------------------------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNH
G---LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVCGKA-------MTDES
--DTCSSQKTEVSTVS-STQVGPN------------------------------------
---------------------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------DLAETVIA-STIS
IVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDA
KLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
MIVLMVTCCITPLSIIVLCYLQVWLAI---------------------------------
------------------------------------------------------------
------------------------------RAVAKQQK----------ESESTQKA----
-------------------------EKEVTRMVVVMVLAFC-------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------------------------------------------------------MA
QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNY-HIAPRWV--------
-YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STIS
VVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDA
KLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
MIVLMVTCCITPLSIIVLCYLQVWLAI---------------------------------
------------------------------------------------------------
------------------------------RAVAKQQK----------ESESTQKA----
-------------------------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY
P---FHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDD
GSELSSASKTEVSSV---SSVSPA------------------------------------
---------------------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
----------------------------------------------------------MA
QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNY-HIAPRWV--------
-YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STIS
IVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDA
KLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSY
MIVLMVTCCIIPLAIIMLCYLQVWLAI---------------------------------
------------------------------------------------------------
------------------------------RAVAKQQK----------ESESTQKA----
-------------------------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY
A---FHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDD
GSELSSASKTEVSSV---SSVSPA------------------------------------
---------------------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------------------------------------------------------MT
EAWNVAVFAARRSRDD-DDTTRGSVFTYTNTNN-TRGPFEGPNY-HIAPRWV--------
-YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STIS
VFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDS
KLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSF
MLTLMITCCFLPLFIIIVCYLQVWMAI---------------------------------
------------------------------------------------------------
------------------------------RAVAAQQK----------ESESTQKA----
-------------------------EREVSRMVVVMIVAFCICWGPYASFVSFAAANPGY
A---FHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----------GKKVDD
GSEASTTSRTEVSSVS-NSSVAPA------------------------------------
---------------------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
-----------------------------------------------------------M
AAWEAAFAARRRHEE--EDTTRDSVFTYTNSNN-TRGPFEGPNY-HIAPRWV--------
-YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STIS
VINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDG
KLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSY
MVVLMVTCCFFPLAIIILCYLQVWLAI---------------------------------
------------------------------------------------------------
------------------------------RAVAAQQK----------ESESTQKA----
-------------------------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGY
A---FHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----------GKKVDD
GSEVST-SRTEVSSVS-NSSVSPA------------------------------------
---------------------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
---------------------MSSNSSQAPPNG-TPGPFDGPQWPYQAPQST--------
-YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVS
LSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQR
RHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSY
ILSLFVTCFVLPLSLILFSYTNLLLTL---------------------------------
------------------------------------------------------------
------------------------------RAAAAQQK----------EADTTQRA----
-------------------------EREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGI
I---IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQ------PQRTGK
ASPGTPGPHADVTAAGLRNKVMPAHPV---------------------------------
---------------------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
------------------------------------------------------MESGNV
SSSLFGNVSTALRPEARLSA---E-----TRLLGWNVPPEELR--HIPEHWLTYPEPPES
MNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIF
IYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTH
GKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLF
VACIFFFSFVCPTTMITYYYSQIVGHVFSH------------------------------
------------------------------------------------------------
-----------------------------EKALRDQAKKMNVESLRSNVDKNKETA----
-------------------------EIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKT
L---LTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------NEK
APESSAVASTSTTQEPQQTTAA--------------------------------------
---------------------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
------------------------------------------------------MEYHNV
SSVL-GNVSSVLRPDARLSA---E-----SRLLGWNVPPDELR--HIPEHWLIYPEPPES
MNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIF
IYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTH
GKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLF
VACIFFFSFVCPTTMITYYYSQIVGHVFSH------------------------------
------------------------------------------------------------
-----------------------------EKALRDQAKKMNVDSLRSNVDKSKEAA----
-------------------------EIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKT
L---LTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------SEK
APESRAAISTSTTQEQQQTTAA--------------------------------------
---------------------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
------------------------------------------------------ME----
--PLCNASEPPLRPEAR-SSGNGD-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPAS
MHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF
--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTF
TKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLF
VGTIFFFSFVCPTLMILYYYSQIVGHVFSH------------------------------
------------------------------------------------------------
-----------------------------EKALREQAKKMNVESLRSNVDKSKETA----
-------------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS
L---LTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------NEK
SGEISSAQSTTTQEQ-QQTTAA--------------------------------------
---------------------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
------------------------------------------------------MD----
--ALCNASEPPLRPEARMSSGSDE-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPAS
MHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF
IYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTF
TKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLF
VGTIFLFSFVVPTLMILYYYSQIVGHVFNH------------------------------
------------------------------------------------------------
-----------------------------EKALREQAKKMNVESLRSNVDKSKETA----
-------------------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKS
L---LTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------NEK
SGEASSAQSTTTQEQTQQTSAA--------------------------------------
---------------------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
---MTNATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP--YVHQHWYNYPPVNPM
WHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFF
TYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTT
GKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSY
NIFIFVFDYFLPAAIIVFSYVFIVKAIFAH------------------------------
------------------------------------------------------------
-----------------------------EAAMRAQAKKMNVSTLRS-NEADAQRA----
-------------------------EIRIAKTALVNVSLWFICWTPYALISLKGVMGDTS
G---ITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HETETK
SNDDSQSNSTVAQDKA--------------------------------------------
---------------------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
---MANVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH--MVLDHWYNYPPVNPM
WHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPF
CYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQ
GKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITY
NICIFIFDFFLPASVIVFSYVFIVKAIFAH------------------------------
------------------------------------------------------------
-----------------------------EAAMRAQAKKMNVTNLRS-NEAETQRA----
-------------------------EIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAE
G---ITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HEKDPN
DVEENQSSNTQTQEKS--------------------------------------------
---------------------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
---------------------------------------------------------MES
FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPI
WAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
PLALGKM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSY
LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
------------------------------------------------------------
-----------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA----
-------------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E
G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
K-SSDAQSQATASEAESKA-----------------------------------------
---------------------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
---------------------------------------------------------MES
FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPI
WAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
PLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSY
LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
------------------------------------------------------------
-----------------------------EKAMREQAKKMNVKSLRS-SEDAEKSA----
-------------------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-E
G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
K-SSDAQSQATASEAESKA-----------------------------------------
---------------------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
---------------------------------------------------------MDS
FAAVATQLGPQFA-----APS--------NGSVVDKVTPDMAH--LISPYWDQFPAMDPI
WAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMM
GINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTI
PLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSY
LIFYSIFVYYIPLFLICYSYWFIIAAVSAH------------------------------
------------------------------------------------------------
-----------------------------EKAMREQAKKMNVKSLRS-SEDADKSA----
-------------------------EGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-E
G---LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDG
K-SSEAQSQATTSEAESKA-----------------------------------------
---------------------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
----------------------------------------------------MERSHLPE
TPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLPDMAH--LVNPYWSRFAPMDPM
MSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVM
IINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTI
KTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSY
LITYSLFVYYTPLFLICYSYWFIIAAVAAH------------------------------
------------------------------------------------------------
-----------------------------EKAMREQAKKMNVKSLRS-SEDCDKSA----
-------------------------EGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-D
G---LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GNTDEP
KPDAPASDTETTSEADSKA-----------------------------------------
---------------------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
----------------------------------------------------MERSLLPE
PPLAMALLGPRFE-----AQTGG------NRSVLDNVLPDMAP--LVNPHWSRFAPMDPT
MSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVM
IINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTI
KTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSY
LITYSLFVYYTPLFMICYSYWFIIATVAAH------------------------------
------------------------------------------------------------
-----------------------------EKAMRDQAKKMNVKSLRS-SEDCDKSA----
-------------------------ENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-D
G---LTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GTTDEP
KPDAPPSDTETTSEAESKD-----------------------------------------
---------------------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
------------------------------------------------------------
---MIAVSGPSYE-----AFSYGGQARFNNQTVVDKVPPDMLH--LIDANWYQYPPLNPM
WHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPM
VINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSI
NGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASY
LVCYGIWVYFVPLFLIIYSYWFIIQAVAAH------------------------------
------------------------------------------------------------
-----------------------------EKNMREQAKKMNVASLRS-SENQNTSA----
-------------------------ECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-V
K---ISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------AAEPS
SDAVSTTSGTTTVTDNEKSNA---------------------------------------
---------------------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------------------------------------------
-----MANQLSYS-----SLGWPYQP---NASVVDTMPKEMLY--MIHEHWYAFPPMNPL
WYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTM
TSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTH
KKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASY
VVIYGLAVYFLPLITMIYCYFFIVHAVAEH------------------------------
------------------------------------------------------------
-----------------------------EKQLREQAKKMNVASLRANADQQKQSA----
-------------------------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGT
R---LTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GSGESG
SDVKSEASATTTMEEKPKIPEA--------------------------------------
---------------------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------------------
----------MVESTTLVNQTWWY-----NPTVD------------IHPHWAKFDPIPDA
VYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLK
TISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSH
RRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSF
ILCMYFCGFMLPIIIIAFCYFNIVMSVSNH------------------------------
------------------------------------------------------------
-----------------------------EKEMAAMAKRLNAKELR--KAQAGASA----
-------------------------EMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAE
W---VTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDA
NDAEEEVVASER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQ
GAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------------------------------------------
-----------MGRDLRDNETWWY-----NPSIV------------VHPHWREFDQVPDA
VYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLM
TISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSH
RRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSN
ILCMFILGFFGPILIIFFCYFNIVMSVSNH------------------------------
------------------------------------------------------------
-----------------------------EKEMAAMAKRLNAKELR--KAQAGANA----
-------------------------EMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLE
W---VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDD
KDAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQ
GY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS-
--EVTASPAPTW------------DAPPDNASGCGEQIN-----------------YGRV
EKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
------------------KSAAKHKFPGFPRVEPDSVIAL--------------------
-----------------------------NGIVKLQKEVEECANLSRLL-----------
-------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMH
EALKLAERPERPEFVLQNADYCRKKGHDS-------------------------------
---------------------------------------------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
-----------------------------------------------------MPHLLSG
FLEVTASPAPTW------------DAPPDNVSGCGEQIN-----------------YGRV
EKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
------------------KSAAKHKFPGFPRVQPESVISL--------------------
-----------------------------NGVVKLQKEVEECANLSRLL-----------
-------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINRKLSAAGMH
EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
---------------------------------------------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
-----------------------------------------------------MPHLLSG
FLEVTASPAPTW------------DAPPDNVSGCGEQIN-----------------YGRV
EKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFV
SVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNG
KCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GY
TIYSTAVAFYIPMSVMLFMYYQIYKAAR--------------------------------
------------------KSAAKHKFPGFPRVQPESVISL--------------------
-----------------------------NGVVKLQKEVEECANLSRLL-----------
-------------KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT
SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMH
EALKLAERPERSEFVLQNSDHCGKKGHDT-------------------------------
---------------------------------------------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDVLSPGQ-------GN----------------------NTTSPPAPFET
GGNTTGISDVTV-----------------------------------------------S
YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMA
ALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTP
RRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GY
TIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------------------
------------TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGSR----
-----NWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PT
PCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CES
SCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ----------
------------------------------------------------------------
---------------------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDVFSFGQ-------GN----------------------NTTASQEPFGT
GGNVTSISDVTF-----------------------------------------------S
YQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMA
ALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTP
RRAAALISLTWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GY
TIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK---------------------------
------------TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGSG----
-----DWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SN
SYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CES
SCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR----------
------------------------------------------------------------
---------------------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN-----MTDDRYWSLTVYSHE
HLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLS
VVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSA
RRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GY
TIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSV
VSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS-----
-----SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS----
---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP
E-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR--------
------------------------------------------------------------
---------------------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN-----MTDDRYWSLTVYSHE
HLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLS
VVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSA
RRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GY
TIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSV
VSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS-----
-----SERLKQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS----
---------RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP
E-G-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR--------
------------------------------------------------------------
---------------------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-MEGAEGQEELDWEAL--YLRLP--LQ----------------------NCSWNSTGWEP
NWNVTVVPNTTW---------WQASAPFDTPAALVRAAAK--------------------
-----AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLG
AVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTA
KRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GY
QIFATASSFYVPVLIILILYWRIYQTARKRIR----------------------------
-----------------RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIAAA
VVAVIGRPLPTISETTTTGFTNVSS----NNTS---PEKQSCANGLEADPPTTGYGAVAA
AYYPSLVRRKPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDC
E---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRAPQ-----
------------------------------------------------------------
---------------------------------------------------
