>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------------------------------------------
---------MNGTE--GDNFYVP----FSNKTGLARSPYEYPQYYLAEPWK---------
YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTM
YTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNT
HAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYV
VYMFVVHFLVPFVIIFFCYGRLLCTV----------------------------------
------------------------------------------------------------
-------------------KEAAAAQQ-----------------------------ESAS
TQKA----------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFT---HQGSD-FGATFM
TLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCCGKN------PLGDDE--SGASTSKT
EVSSVS-TSPVSPA----------------------------------------------
-----------------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------------------------------------------
---------MNGTE--GPNFYVP----FSNITGVVRSPFEQPQYYLAEPWQ---------
FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTL
YTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGEN
HAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFV
IYMFVVHFTIPMIVIFFCYGQLVFTV----------------------------------
------------------------------------------------------------
-------------------KEAAAQQQ-----------------------------ESAT
TQKA----------EKEVTRMVIIMVIFFLICWLPYASVAMYIFT---HQGSN-FGPIFM
TLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCCGKN------PLGDDE--ASATASKT
ETSQ------VAPA----------------------------------------------
-----------------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------------------------------------------
---------MNGTE--GINFYVP----MSNKTGVVRSPFEYPQYYLAEPWK---------
YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTF
YTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSAT
HAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYV
LYMFVIHFIIPVVVIFFSYGRLICKV----------------------------------
------------------------------------------------------------
-------------------REAAAQQQ-----------------------------ESAT
TQKA----------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFT---NKGAD-FTATLM
AVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICCGKN------PFGDEDVSSTVSQSKT
EVSSVS-SSQVSPA----------------------------------------------
-----------------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------------------------------------------
---------MNGTE--GKNFYVP----MSNRTGLVRSPFEYPQYYLAEPWQ---------
FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTF
YTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSS
HAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYV
IYMFVCHFILPVAVIFFTYGRLVCTV----------------------------------
------------------------------------------------------------
-------------------KAAAAQQQ-----------------------------DSAS
TQKA----------EREVTKMVILMVFGFLIAWTPYATVAAWIFF---NKGAD-FSAKFM
AIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFCGKN------PLGDDE-SSTVSTSKT
EVSS------VSPA----------------------------------------------
-----------------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------------------------------------------
---------MNGTE--GNNFYVP----LSNRTGLVRSPFEYPQYYLAEPWQ---------
FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTF
YTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSST
HASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYV
LYMFICHFILPVTIIFFTYGRLVCTV----------------------------------
------------------------------------------------------------
-------------------KAAAAQQQ-----------------------------DSAS
TQKA----------EREVTKMVILMVLGFLVAWTPYATVAAWIFF---NKGAA-FSAQFM
AIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFCGKN------PLGDEE-SSTVSTSKT
EVSS------VSPA----------------------------------------------
-----------------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------------------------------------------
---------MKQVPEFHEDFYIPIPLDINNLS--AYSPFLVPQDHLGNQGI---------
FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSF
YSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTP
HAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYV
MFLFCFCFAVPFGTIVFCYGQLLITL----------------------------------
------------------------------------------------------------
-------------------KLAAKAQA-----------------------------DSAS
TQKA----------EREVTKMVVVMVLGFLVCWAPYASFSLWIVS---HRGEE-FDLRMA
TIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVCGKN-------IEEDE--ASTSSQVT
QVSS------VAPEK---------------------------------------------
-----------------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
---------MRKMS--EEEFYL-----FKNISSV--GPWDGPQYHIAPVWA---------
FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVF
VASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSK
HALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYT
WFLFIFCFIVPLSLICFSYTQLLRAL----------------------------------
------------------------------------------------------------
-------------------KAVAAQQQ-----------------------------ESAT
TQKA----------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVN---NRNHG-LDLRLV
TIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVCGKA-------MTDES--DTCSSQKT
EVSTVS-STQVGPN----------------------------------------------
-----------------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------DLAETVIA-STISI
VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAK
LAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCITPLSIIVLCYLQVWLAI----------------------------------
------------------------------------------------------------
-------------------RAVAKQQK-----------------------------ESES
TQKA----------EKEVTRMVVVMVLAFC------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
----------------------------------------------------------MA
QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNYHIAPRWV---------
YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISV
VNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAK
LAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCITPLSIIVLCYLQVWLAI----------------------------------
------------------------------------------------------------
-------------------RAVAKQQK-----------------------------ESES
TQKA----------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAA---NPGYP-FHPLMA
ALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDDGSELSSASKT
EVSSV---SSVSPA----------------------------------------------
-----------------------------------------
>    10== Z68193   1 human Red Opsin <>[]
----------------------------------------------------------MA
QQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNS-TRGPFEGPNYHIAPRWV---------
YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISI
VNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAK
LAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYM
IVLMVTCCIIPLAIIMLCYLQVWLAI----------------------------------
------------------------------------------------------------
-------------------RAVAKQQK-----------------------------ESES
TQKA----------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAA---NPGYA-FHPLMA
ALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----------GKKVDDGSELSSASKT
EVSSV---SSVSPA----------------------------------------------
-----------------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
----------------------------------------------------------MT
EAWNVAVFAARRSRD-DDDTTRGSVFTYTNTNN-TRGPFEGPNYHIAPRWV---------
YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISV
FNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSK
LAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFM
LTLMITCCFLPLFIIIVCYLQVWMAI----------------------------------
------------------------------------------------------------
-------------------RAVAAQQK-----------------------------ESES
TQKA----------EREVSRMVVVMIVAFCICWGPYASFVSFAAA---NPGYA-FHPLAA
ALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----------GKKVDDGSEASTTSRT
EVSSVS-NSSVAPA----------------------------------------------
-----------------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
-----------------------------------------------------------M
AAWEAAFAARRRHE--EEDTTRDSVFTYTNSNN-TRGPFEGPNYHIAPRWV---------
YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISV
INQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGK
LAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYM
VVLMVTCCFFPLAIIILCYLQVWLAI----------------------------------
------------------------------------------------------------
-------------------RAVAAQQK-----------------------------ESES
TQKA----------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAA---NPGYA-FHPLAA
ALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----------GKKVDDGSEVST-SRT
EVSSVS-NSSVSPA----------------------------------------------
-----------------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
----------------------------MSSNSSQAPPNGTPGPFDGPQWP--YQAPQST
YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSL
SNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRR
HAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGS--NNNSYI
LSLFVTCFVLPLSLILFSYTNLLLTL----------------------------------
------------------------------------------------------------
-------------------RAAAAQQK-----------------------------EADT
TQRA----------EREVTRMVIVMVMAFLLCWLPYSTFALVVAT---HKGII-IQPVLA
SLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQ------PQRTGKASPGTPGPHA
DVTAAGLRNKVMPAHPV-------------------------------------------
-----------------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
------------------------------------------------------MESGNV
SSSLFGNVSTALRPEARLSAE--------TRLLGWNVPPEELR-HIPEHWLTYPEPPESM
NYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFI
YNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHG
KAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFV
ACIFFFSFVCPTTMITYYYSQIVGHVFSH-------------------------------
------------------------------------------------------------
------------------EKALRDQAKKMNVESLRS-------------------NVDKN
KETA----------EIRIAKAAITICFLFFCSWTPYGVMSLIGAF---GDKTL-LTPGAT
MIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL---------NEKAPESSAVAST
STTQEPQQTTAA------------------------------------------------
-----------------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
------------------------------------------------------MEYHNV
S-SVLGNVSSVLRPDARLSAE--------SRLLGWNVPPDELR-HIPEHWLIYPEPPESM
NYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFI
YNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHG
KAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFV
ACIFFFSFVCPTTMITYYYSQIVGHVFSH-------------------------------
------------------------------------------------------------
------------------EKALRDQAKKMNVDSLRS-------------------NVDKS
KEAA----------EIRIAKAAITICFLFFASWTPYGVMSLIGAF---GDKTL-LTPGAT
MIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI---------SEKAPESRAAIST
STTQEQQQTTAA------------------------------------------------
-----------------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
------------------------------------------------------ME----
--PLCNASEPPLRPEARSSGNGD------LQFLGWNVPPDQIQ-YIPEHWLTQLEPPASM
HYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF-
-NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
KAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFV
GTIFFFSFVCPTLMILYYYSQIVGHVFSH-------------------------------
------------------------------------------------------------
------------------EKALREQAKKMNVESLRS-------------------NVDKS
KETA----------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-LTQGAT
MIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV---------NEKSGEISSAQST
TTQEQ-QQTTAA------------------------------------------------
-----------------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
------------------------------------------------------MD----
--ALCNASEPPLRPEARMSSGSDE-----LQFLGWNVPPDQIQ-YIPEHWLTQLEPPASM
HYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFI
YNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFT
KAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFV
GTIFLFSFVVPTLMILYYYSQIVGHVFNH-------------------------------
------------------------------------------------------------
------------------EKALREQAKKMNVESLRS-------------------NVDKS
KETA----------EIRIAKAAITICFLFFVSWTPYGVMSLIGAF---GDKSL-LTPGAT
MIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV---------NEKSGEASSAQST
TTQEQTQQTSAA------------------------------------------------
-----------------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
---MTNATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP-YVHQHWYNYPPVNPMW
HYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFT
YNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTG
KAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYN
IFIFVFDYFLPAAIIVFSYVFIVKAIFAH-------------------------------
------------------------------------------------------------
------------------EAAMRAQAKKMNVSTLRS--------------------NEAD
AQRA----------EIRIAKTALVNVSLWFICWTPYALISLKGVM---GDTSG-ITPLVS
TLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV------HETETKSNDDSQSNST
VAQDKA------------------------------------------------------
-----------------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
------------------------------------------------------------
---MANVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH-MVLDHWYNYPPVNPMW
HYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFC
YNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQG
KATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYN
ICIFIFDFFLPASVIVFSYVFIVKAIFAH-------------------------------
------------------------------------------------------------
------------------EAAMRAQAKKMNVTNLRS--------------------NEAE
TQRA----------EIRIAKTALVNVSLWFICWTPYAAITIQGLL---GNAEG-ITPLLT
TLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV------HEKDPNDVEENQSSNT
QTQEKS------------------------------------------------------
-----------------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
---------------------------------------------------------MES
FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH-LISPYWNQFPAMDPIW
AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
LALGKM---------------------------YVPEGNLTSCGIDYLE--RDWNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
------------------------------------------------------------
------------------EKAMREQAKKMNVKSLRS--------------------SEDA
EKSA----------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSDAQSQA
TASEAESKA---------------------------------------------------
-----------------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
---------------------------------------------------------MES
FAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH-LISPYWNQFPAMDPIW
AKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
LALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
------------------------------------------------------------
------------------EKAMREQAKKMNVKSLRS--------------------SEDA
EKSA----------EGKLAKVALVTITLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSDAQSQA
TASEAESKA---------------------------------------------------
-----------------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
---------------------------------------------------------MDS
FAAVATQLGPQFA-----APS--------NGSVVDKVTPDMAH-LISPYWDQFPAMDPIW
AKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMG
INLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIP
LALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYL
IFYSIFVYYIPLFLICYSYWFIIAAVSAH-------------------------------
------------------------------------------------------------
------------------EKAMREQAKKMNVKSLRS--------------------SEDA
DKSA----------EGKLAKVALVTISLWFMAWTPYLVINCMGLF---KF-EG-LTPLNT
IWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF------GKVDDGK-SSEAQSQA
TTSEAESKA---------------------------------------------------
-----------------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
----------------------------------------------------MERSHLPE
TPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLPDMAH-LVNPYWSRFAPMDPMM
SKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
INFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIK
TSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYL
ITYSLFVYYTPLFLICYSYWFIIAAVAAH-------------------------------
------------------------------------------------------------
------------------EKAMREQAKKMNVKSLRS--------------------SEDC
DKSA----------EGKLAKVALTTISLWFMAWTPYLVICYFGLF---KI-DG-LTPLTT
IWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF------GNTDEPKPDAPASDTE
TTSEADSKA---------------------------------------------------
-----------------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
----------------------------------------------------MERSLLPE
PPLAMALLGPRFE-----AQTGG------NRSVLDNVLPDMAP-LVNPHWSRFAPMDPTM
SKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMI
INFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIK
TSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYL
ITYSLFVYYTPLFMICYSYWFIIATVAAH-------------------------------
------------------------------------------------------------
------------------EKAMRDQAKKMNVKSLRS--------------------SEDC
DKSA----------ENKLAKVALTTISLWFMAWTPYLIICYFGLF---KI-DG-LTPLTT
IWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC------GTTDEPKPDAPPSDTE
TTSEAESKD---------------------------------------------------
-----------------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
------------------------------------------------------------
---MIAVSGPSYE-----AFSYGGQARFNNQTVVDKVPPDMLH-LIDANWYQYPPLNPMW
HGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMV
INCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSIN
GALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYL
VCYGIWVYFVPLFLIIYSYWFIIQAVAAH-------------------------------
------------------------------------------------------------
------------------EKNMREQAKKMNVASLRS--------------------SENQ
NTSA----------ECKLAKVALMTISLWFMAWTPYLVINFSGIF---NL-VK-ISPLFT
IWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC-------AAEPSSDAVSTTSGT
TTVTDNEKSNA-------------------------------------------------
-----------------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
------------------------------------------------------------
-----MANQLSYS-----SLGWPYQP---NASVVDTMPKEMLY-MIHEHWYAFPPMNPLW
YSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMT
SNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHK
KATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYV
VIYGLAVYFLPLITMIYCYFFIVHAVAEH-------------------------------
------------------------------------------------------------
------------------EKQLREQAKKMNVASLRA-------------------NADQQ
KQSA----------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVF---SSGTR-LTPLAT
IWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC------GSGESGSDVKSEASAT
TTMEEKPKIPEA------------------------------------------------
-----------------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------------------
----------MVESTTLVNQTWWY-----NPTVD-----------IHPHWAKFDPIPDAV
YYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKT
ISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHR
RAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFI
LCMYFCGFMLPIIIIAFCYFNIVMSVSNH-------------------------------
------------------------------------------------------------
------------------EKEMAAMAKRLNAKELR---------------------KAQA
GASA----------EMKLAKISMVIITQFMLSWSPYAIIALLAQF---GPAEW-VTPYAA
ELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAEEEVVAS
ER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGYP
PQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------------------------------------------
-----------MGRDLRDNETWWY-----NPSIV-----------VHPHWREFDQVPDAV
YYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMT
ISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHR
RAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNI
LCMFILGFFGPILIIFFCYFNIVMSVSNH-------------------------------
------------------------------------------------------------
------------------EKEMAAMAKRLNAKELR---------------------KAQA
GANA----------EMRLAKISIVIVSQFLLSWSPYAVVALLAQF---GPLEW-VTPYAA
QLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAG
ESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQGYP
PQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS-
--EVTASPAPTWDAPPDNASGCGEQINYGRVE----------------------------
KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIAL-----------
------------------------------------------------------------
------------------NGIVKLQKEVEECANLSR-------------------LLKHE
RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
RTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPE
RPEFVLQNADYCRKKGHDS-----------------------------------------
-----------------------------------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
-----------------------------------------------------MPHLLSG
FLEVTASPAPTWDAPPDNVSGCGEQINYGRVE----------------------------
KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL-----------
------------------------------------------------------------
------------------NGVVKLQKEVEECANLSR-------------------LLKHE
RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
RTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNINRKLSAAGMHEALKLAERPE
RSEFVLQNSDHCGKKGHDT-----------------------------------------
-----------------------------------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
-----------------------------------------------------MPHLLSG
FLEVTASPAPTWDAPPDNVSGCGEQINYGRVE----------------------------
KVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVS
VTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGK
CMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISL-----------
------------------------------------------------------------
------------------NGVVKLQKEVEECANLSR-------------------LLKHE
RKNI-----SIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC-IPLWVE
RTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPE
RSEFVLQNSDHCGKKGHDT-----------------------------------------
-----------------------------------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPGQGN---------------------------------------NTTSPPAPFET
GGNTTGISDVTVSY----------------------------------------------
QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
-----------TVKKVEKTGADTRHGASPAPQPKKS----------VNGESGSRNWRLGV
ESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCA--PASFERKN
ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCHMPTLLG
AIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ--------------------
------------------------------------------------------------
-----------------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
MDVFSFGQGN---------------------------------------NTTASQEPFGT
GGNVTSISDVTFSY----------------------------------------------
QVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAA
LYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPR
RAAALISLTWLIGFLI-SIPPMLG-WRTP---EDRSDPDACTISKDH----------GYT
IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
-----------TVRKVEKKGAGTSLGTSSAPPPKKS----------LNGQPGSGDWRRCA
ENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYA--PACLERKN
ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF---CESSCHMPALLG
AIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR--------------------
------------------------------------------------------------
-----------------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN----MTDDRYWSLTVYSHEH
LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQ
IQIETAEAFANGCA----EEASIAMLERQ-CNNGKK-------------------ISSND
TPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-IPPFAR
SFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR------------------
------------------------------------------------------------
-----------------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSGLR----------------------STGLTTPGLSP
TGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATN----MTDDRYWSLTVYSHEH
LVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSV
VSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSAR
RILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYT
IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQ
IQIETAEAFANGCA----EEASIAMLERQ-CNNGKK-------------------ISSND
TPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF---VDPEG-IPPFAR
SFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR------------------
------------------------------------------------------------
-----------------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
---------------------------MEGAEGQEELDWEALYLRLPLQNCSWNSTGWEP
NWNVTVVPNTTWWQ--------------------ASAPFDTPAALVR-------------
AAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGA
VYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAK
RVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQ
IFATASSFYVPVLIILILYWRIYQTARKRIRR----------------------------
-----------------RRGATARGGVGPPPVPAGGALVA------GGGSGGIAAAVVAV
IGRPLPTISETTTTGFTNVSSNNTSPEKQSCANGLEADPPTTGYGAVAAAYYPSLVRRKP
KEAA------DSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT---CDCE--VSPVLT
SLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRAPQ---------------
------------------------------------------------------------
-----------------------------------------
