>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
MN----------------------GTEGDNFYVPFSNKTGLA--RSPYEYPQY-------
------------------YLAEPW-------------------KYSALAAYMFFLILVGF
PVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GYFV--FGPT
MCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIMGVAFTWIMALAC
-AAPPLV-GWS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHFLVPFVIIF
FCYGRLLCTVKEAAAAQQESA---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEKEVTRMVVLMVI
GFLVCWVPYASVAFYIFT--HQGSD-FGATFMTLPAFFAKSSALYNPVIYILMNKQFRNC
MITTL-----CCGKNPLGDDESG--AS-TSKTEVS-------------------------
------------------------------------------------------------
-SVS-TSPVSPA---
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
MN----------------------GTEGPNFYVPFSNITGVV--RSPFEQPQY-------
------------------YLAEPW-------------------QFSMLAAYMFLLIVLGF
PINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GYFV--FGPT
GCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIMGVAFTWVMALAC
-AAPPLV-GWS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIF
FCYGQLVFTVKEAAAQQQESA---------------------------------------
------------------------------------------------------------
------------------------------------------TTQKAEKEVTRMVIIMVI
FFLICWLPYASVAMYIFT--HQGSN-FGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNC
MLTSL-----CCGKNPLGDDEAS--AT-ASKTETS-------------------------
------------------------------------------------------------
-QVA-PA--------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
MN----------------------GTEGINFYVPMSNKTGVV--RSPFEYPQY-------
------------------YLAEPW-------------------KYRLVCCYIFFLISTGL
PINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GYFV--FGPV
GCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMMGIAFTWVMAFSC
-AAPPLF-GWS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHFIIPVVVIF
FSYGRLICKVREAAAQQQESA---------------------------------------
------------------------------------------------------------
------------------------------------------TTQKAEKEVTRMVILMVL
GFMLAWTPYAVVAFWIFT--NKGAD-FTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNC
MITTI-----CCGKNPFGDEDVSSTVS-QSKTEVS-------------------------
------------------------------------------------------------
-SVS-SSQVSPA---
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
MN----------------------GTEGKNFYVPMSNRTGLV--RSPFEYPQY-------
------------------YLAEPW-------------------QFKILALYLFFLMSMGL
PINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GYFV--LGPT
GCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFAGIAFTWVMALAC
-AAPPLF-GWS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHFILPVAVIF
FTYGRLVCTVKAAAAQQQDSA---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEREVTKMVILMVF
GFLIAWTPYATVAAWIFF--NKGAD-FSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNC
MLTTI-----FCGKNPLGDDESS-TVS-TSKTEVS-------------------------
------------------------------------------------------------
-SVS-PA--------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
MN----------------------GTEGNNFYVPLSNRTGLV--RSPFEYPQY-------
------------------YLAEPW-------------------QFKLLAVYMFFLICLGL
PINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GYFA--LGPT
GCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASAGIAFTWVMAMAC
-AAPPLV-GWS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHFILPVTIIF
FTYGRLVCTVKAAAAQQQDSA---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEREVTKMVILMVL
GFLVAWTPYATVAAWIFF--NKGAA-FSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSC
MLTTL-----FCGKNPLGDEESS-TVS-TSKTEVS-------------------------
------------------------------------------------------------
-SVS-PA--------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
MK--------------------QVPEFHEDFYIPIPLDINNLSAYSPFLVPQD-------
------------------HLGNQG-------------------IFMAMSVFMFFIFIGGA
SINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RYFI--FGAT
ACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIAGCILPWISALAA
-SLPPLF-GWS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCFAVPFGTIV
FCYGQLLITLKLAAKAQADSA---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEREVTKMVVVMVL
GFLVCWAPYASFSLWIVS--HRGEE-FDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSC
MMKMV------CGKN-IEEDEAS--TS-SQVTQVS-------------------------
------------------------------------------------------------
-SVA-PEK-------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
MR----------------------KMSEEEFYL-----FKNISSVGPWDGPQY-------
------------------HIAPVW-------------------AFYLQAAFMGTVFLIGF
PLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GYFV--FGRH
VCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALTVVLATWTIGIGV
-SIPPFF-GWS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLIC
FSYTQLLRALKAVAAQQQESA---------------------------------------
------------------------------------------------------------
------------------------------------------TTQKAEREVSRMVVVMVG
SFCVCYVPYAAFAMYMVN--NRNHG-LDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQAC
IMKMV------CGKA---MTDESDTCS-SQKTEVS-------------------------
------------------------------------------------------------
-TVS-STQVGPN---
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------DLAETVIA-STISIVNQVS-GYFV--LGHP
MCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW
-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIV
LCYLQVWLAIRAVAKQQKESE---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEKEVTRMVVVMVL
AFC---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLAGRHPQDS-YEDSTQ--SSIFTY-----TNSNSTRGPFEGPNY-------
------------------HIAPRW-------------------VYHLTSVWMIFVVIASV
FTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GYFV--LGHP
MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIVGIAFSWIWAAVW
-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIV
LCYLQVWLAIRAVAKQQKESE---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEKEVTRMVVVMVL
AFCFCWGPYAFFACFAAA--NPGYP-FHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNC
ILQLF----------GKKVDDGSELSS-ASKTEVS-------------------------
------------------------------------------------------------
-SVS---SVSPA---
>    10== Z68193   1 human Red Opsin <>[]
MAQQWSLQRLAGRHPQDS-YEDSTQ--SSIFTY-----TNSNSTRGPFEGPNY-------
------------------HIAPRW-------------------VYHLTSVWMIFVVTASV
FTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GYFV--LGHP
MCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIVGIAFSWIWSAVW
-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIM
LCYLQVWLAIRAVAKQQKESE---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEKEVTRMVVVMIF
AYCVCWGPYTFFACFAAA--NPGYA-FHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC
ILQLF----------GKKVDDGSELSS-ASKTEVS-------------------------
------------------------------------------------------------
-SVS---SVSPA---
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD--DDTTR--GSVFTY-----TNTNNTRGPFEGPNY-------
------------------HIAPRW-------------------VYNLVSFFMIIVVIASC
FTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GYFI--LGHP
LCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAIIGIVFSWVWAWGW
-SAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIII
VCYLQVWMAIRAVAAQQKESE---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEREVSRMVVVMIV
AFCICWGPYASFVSFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNC
IMQLF----------GKKVDDGSEAST-TSRTEVS-------------------------
------------------------------------------------------------
-SVS-NSSVAPA---
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWE-AAFAARRRHEE--EDTTR--DSVFTY-----TNSNNTRGPFEGPNY-------
------------------HIAPRW-------------------VYNLTSVWMIFVVAASV
FTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GYFI--LGHP
MCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVAGILFSWLWSCAW
-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCCFFPLAIII
LCYLQVWLAIRAVAAQQKESE---------------------------------------
------------------------------------------------------------
------------------------------------------STQKAEKEVSRMVVVMIV
AYCFCWGPYTFFACFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNC
ILQLF----------GKKVDDGSEVST--SRTEVS-------------------------
------------------------------------------------------------
-SVS-NSSVSPA---
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
MS-------------------------------SNSSQAPPNGTPGPFDGPQWP------
------------------YQAPQS-------------------TYVGVAVLMGTVVACAS
VVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GFFV--FGRR
MCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVSGCAFTWGWALLW
-SAPPLL-GWS-----SYVPEGLRTSCGPNWYTGGS--NNNSYILSLFVTCFVLPLSLIL
FSYTNLLLTLRAAAAQQKEAD---------------------------------------
------------------------------------------------------------
------------------------------------------TTQRAEREVTRMVIVMVM
AFLLCWLPYSTFALVVAT--HKGII-IQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSC
LLEML-----CCGYQPQRTGKASPGTP-GPHADVT-------------------------
------------------------------------------------------------
-AAGLRNKVMPAHPV
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGNVSSSLFGNVSTALRPEARLSAE----------TRLLGWNVPPEELR---------
------------------HIPEHWLTYP----------EPPESMNYLLGTLYIFFTLMSM
LGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QGYA--LGHL
GCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW
-VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMIT
YYYSQIVGHVFSHEKALRDQAKKMNVESLR------------------------------
------------------------------------------------------------
-------------------------------------SNVDKNKETAEIRIAKAAITICF
LFFCSWTPYGVMSLIGAF--GDKTL-LTPGATMIPACACKMVACIDPFVYAISHPRYRME
LQKRCPWL--ALNEKAPESSAVASTST-TQEPQQT-------------------------
------------------------------------------------------------
-TAA-----------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
MEYHNVSSVL-GNVSSVLRPDARLSAE----------SRLLGWNVPPDELR---------
------------------HIPEHWLIYP----------EPPESMNYLLGTLYIFFTVISM
IGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QGYA--LGHL
GCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW
-VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIFFFSFVCPTTMIT
YYYSQIVGHVFSHEKALRDQAKKMNVDSLR------------------------------
------------------------------------------------------------
-------------------------------------SNVDKSKEAAEIRIAKAAITICF
LFFASWTPYGVMSLIGAF--GDKTL-LTPGATMIPACTCKMVACIDPFVYAISHPRYRME
LQKRCPWL--AISEKAPESRAAISTST-TQEQQQT-------------------------
------------------------------------------------------------
-TAA-----------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
ME------PLCNASEPPLRPEAR-SSGNGD-------LQFLGWNVPPDQIQ---------
------------------YIPEHWLTQL----------EPPASMHYMLGVFYIFLFCAST
VGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RGFAIYLGNT
WCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW
-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFFFSFVCPTLMIL
YYYSQIVGHVFSHEKALREQAKKMNVESLR------------------------------
------------------------------------------------------------
-------------------------------------SNVDKSKETAEIRIAKAAITICF
LFFVSWTPYGVMSLIGAF--GDKSL-LTQGATMIPACTCKLVACIDPFVYAISHPRYRLE
LQKRCPWL--GVNEKSGEISSAQSTTT-QEQQQTT-------------------------
------------------------------------------------------------
-AA------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
MD------ALCNASEPPLRPEARMSSGSDE-------LQFLGWNVPPDQIQ---------
------------------YIPEHWLTQL----------EPPASMHYMLGVFYIFLFFAST
LGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RGFA--LGNT
WCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW
-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIFLFSFVVPTLMIL
YYYSQIVGHVFNHEKALREQAKKMNVESLR------------------------------
------------------------------------------------------------
-------------------------------------SNVDKSKETAEIRIAKAAITICF
LFFVSWTPYGVMSLIGAF--GDKSL-LTPGATMIPACTCKLVACIEPFVYAISHPRYRME
LQKRCPWL--GVNEKSGEASSAQSTTT-QEQTQQT-------------------------
------------------------------------------------------------
-SAA-----------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
M-----------TNATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP---------
------------------YVHQHWYNYP----------PVNPMWHYLLGVIYLFLGTVSI
FGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGVWM--FSPQ
YCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVVFALISWVIAIGC
-ALPPFF-GWG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIFVFDYFLPAAIIV
FSYVFIVKAIFAHEAAMRAQAKKMNVSTLR------------------------------
------------------------------------------------------------
-------------------------------------S-NEADAQRAEIRIAKTALVNVS
LWFICWTPYALISLKGVM--GDTSG-ITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLA
ITQHLPWF--CVHETETKSNDDSQSNS-TVAQDKA-------------------------
------------------------------------------------------------
---------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
M-----------ANVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH---------
------------------MVLDHWYNYP----------PVNPMWHYLLGVVYLFLGVISI
AGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGRWM--FSGT
YCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATFMCGLAWVISVGW
-SLPPFF-GWG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIFIFDFFLPASVIV
FSYVFIVKAIFAHEAAMRAQAKKMNVTNLR------------------------------
------------------------------------------------------------
-------------------------------------S-NEAETQRAEIRIAKTALVNVS
LWFICWTPYAAITIQGLL--GNAEG-ITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLA
ITQHLPWF--CVHEKDPNDVEENQSSN-TQTQEKS-------------------------
------------------------------------------------------------
---------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
ME-----SFAVAAAQLGPHFAPLS-------------NGSVVDKVTPDMAH---------
------------------LISPYWNQFP----------AMDPIWAKILTAYMIMIGMISW
CGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPM
MCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKM----------
-----------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLIC
YSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------------------
------------------------------------------------------------
-------------------------------------S-SEDAEKSAEGKLAKVALVTIT
LWFMAWTPYLVINCMGLF---KFEG-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCC--VFGKVDDGKSSDAQSQA-TASEAESKA-----------------------
------------------------------------------------------------
---------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
ME-----SFAVAAAQLGPHFAPLS-------------NGSVVDKVTPDMAH---------
------------------LISPYWNQFP----------AMDPIWAKILTAYMIMIGMISW
CGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPM
MCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSSIW
-CLAPAF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLIC
YSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------------------
------------------------------------------------------------
-------------------------------------S-SEDAEKSAEGKLAKVALVTIT
LWFMAWTPYLVINCMGLF---KFEG-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCC--VFGKVDDGKSSDAQSQA-TASEAESKA-----------------------
------------------------------------------------------------
---------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
MD-----SFAAVATQLGPQFAAPS-------------NGSVVDKVTPDMAH---------
------------------LISPYWDQFP----------AMDPIWAKILTAYMIIIGMISW
CGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ETWV--LGPM
MCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALGKIAYIWFMSTIW
CCLAPVF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYSIFVYYIPLFLIC
YSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------------------
------------------------------------------------------------
-------------------------------------S-SEDADKSAEGKLAKVALVTIS
LWFMAWTPYLVINCMGLF---KFEG-LTPLNTIWGACFAKSAACYNPIVYGISHPKYRLA
LKEKCPCC--VFGKVDDGKSSEAQSQA-TTSEAESKA-----------------------
------------------------------------------------------------
---------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPETPFDLAHSGPRFQAQSSG-----------NGSVLDNVLPDMAH---------
------------------LVNPYWSRFA----------PMDPMMSKILGLFTLAIMIISC
CGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPL
WCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKILFIWMMAVFW
-TVMPLI-GWS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYSLFVYYTPLFLIC
YSYWFIIAAVAAHEKAMREQAKKMNVKSLR------------------------------
------------------------------------------------------------
-------------------------------------S-SEDCDKSAEGKLAKVALTTIS
LWFMAWTPYLVICYFGLF---KIDG-LTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIV
LKEKCPMC--VFGNTDEPKPDAPASDTETTSEADSKA-----------------------
------------------------------------------------------------
---------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSLLPEPPLAMALLGPRFEAQTGG-----------NRSVLDNVLPDMAP---------
------------------LVNPHWSRFA----------PMDPTMSKILGLFTLVILIISC
CGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ETWV--LGPL
WCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIMKIAFIWMMAVFW
-TIMPLI-GWS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYSLFVYYTPLFMIC
YSYWFIIATVAAHEKAMRDQAKKMNVKSLR------------------------------
------------------------------------------------------------
-------------------------------------S-SEDCDKSAENKLAKVALTTIS
LWFMAWTPYLIICYFGLF---KIDG-LTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLV
LKEKCPMC--VCGTTDEPKPDAPPSDTETTSEAESKD-----------------------
------------------------------------------------------------
---------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
M-----------IAVSGPSYEAFSYGGQARFN-----NQTVVDKVPPDMLH---------
------------------LIDANWYQYP----------PLNPMWHGILGFVIGMLGFVSA
MGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ETWV--LGPL
FCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALIRIIAIWLFSLGW
-TIAPMF-GWN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYGIWVYFVPLFLII
YSYWFIIQAVAAHEKNMREQAKKMNVASLR------------------------------
------------------------------------------------------------
-------------------------------------S-SENQNTSAECKLAKVALMTIS
LWFMAWTPYLVINFSGIF---NLVK-ISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAA
LFAKFPSL--ACAA-EPSSDAVSTTSG-TTTVTDNEKSNA--------------------
------------------------------------------------------------
---------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
M------ANQLSYSSLGWPYQP---------------NASVVDTMPKEMLY---------
------------------MIHEHWYAFP----------PMNPLWYSILGVAMIILGIICV
LGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ETWI--LGPF
MCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATLLLLFVWIWSGGW
-TILPFF-GWS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYGLAVYFLPLITMI
YCYFFIVHAVAEHEKQLREQAKKMNVASLR------------------------------
------------------------------------------------------------
-------------------------------------ANADQQKQSAECRLAKVAMMTVG
LWFMAWTPYLIISWAGVF--SSGTR-LTPLATIWGSVFAKANSCYNPIVYGISHPRYKAA
LYQRFPSL--ACGSGESGSDVKSEASA-TTTMEEKPKIPEA-------------------
------------------------------------------------------------
---------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
M-------------------------------VESTTLVNQTWWYNPTV-----------
------------------DIHPHWAKFD----------PIPDAVYYSVGIFIGVVGIIGI
LGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KKWI--FGKV
ACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW
-SVGPVF-NWG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMYFCGFMLPIIIIA
FCYFNIVMSVSNHEKEMAAMAKRLNAKELR------------------------------
------------------------------------------------------------
---------------------------------------KAQAGASAEMKLAKISMVIIT
QFMLSWSPYAIIALLAQF--GPAEW-VTPYAAELPVLFAKASAIHNPIVYSVSHPKFREA
IQTTFPWLLTCCQFDEKECEDANDAEE-EVVASER--GGESRDAAQMKEMMAMMQKMQAQ
QAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAP
QGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
M--------------------------------GRDLRDNETWWYNPSI-----------
------------------VVHPHWREFD----------QVPDAVYYSLGIFIGICGIIGC
GGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KKWI--FGFA
ACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW
-AIGPIF-GWG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMFILGFFGPILIIF
FCYFNIVMSVSNHEKEMAAMAKRLNAKELR------------------------------
------------------------------------------------------------
---------------------------------------KAQAGANAEMRLAKISIVIVS
QFLLSWSPYAVVALLAQF--GPLEW-VTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREA
ISQTFPWVLTCCQFDDKETEDDKDAET-EIPAGESSDAAPSADAAQMKEMMAMMQKMQQQ
QAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQGAPP-----
-AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS---EVTA---
------------------SPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTI
AGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHF
FCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVML
FMYYQIYKAARKSAAKHKFP--------------GFPRVEPDSVIALNGIVKLQKEVEE-
------------------------------------------------------------
---------------------------CANLSRLLKHERKNISIFKREQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTT
YRSLL-----QCQYRNINRKLSAAGMH-EALKLAERPERPEFVLQNADYCRKKGHDS---
------------------------------------------------------------
---------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
M--------------------------------------------PHLLSGFLEVTA---
------------------SPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTI
AGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHF
FCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVML
FMYYQIYKAARKSAAKHKFP--------------GFPRVQPESVISLNGVVKLQKEVEE-
------------------------------------------------------------
---------------------------CANLSRLLKHERKNISIFKREQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPT
SRSLL-----QCQYRNINRKLSAAGMH-EALKLAERPERSEFVLQNSDHCGKKGHDT---
------------------------------------------------------------
---------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
M--------------------------------------------PHLLSGFLEVTA---
------------------SPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTI
AGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGKWI--FGHF
FCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVML
FMYYQIYKAARKSAAKHKFP--------------GFPRVQPESVISLNGVVKLQKEVEE-
------------------------------------------------------------
---------------------------CANLSRLLKHERKNISIFKREQKAATTLGIIVG
AFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTT
YRSLL-----QCQYRNINRKLSAAGMH-EALKLAERPERSEFVLQNSDHCGKKGHDT---
------------------------------------------------------------
---------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPGQGNNTTSPPAPF-----------------------------------------
------------------ETGGNTTGIS----------DVTVSYQVITSLLLGTLIFCAV
LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQV
TCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI
-SIPPML-GWRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLML
VLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKS---------VNGESGSRNW
RLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFER
KNERNA-------------------------------EAKRKMALARERKTVKTLGIIMG
TFILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNA
FKKII-----KCKFCRQ-------------------------------------------
------------------------------------------------------------
---------------
>    33=p A35181 serotonin receptor class 1A - rat
MDVFSFGQGNNTTASQEPF-----------------------------------------
------------------GTGGNVTSIS----------DVTFSYQVITSLLLGTLIFCAV
LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NKWT--LGQV
TCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI
-SIPPML-GWRTP---EDRSDPDACTISKDH----------GYTIYSTFGAFYIPLLLML
VLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKKS---------LNGQPGSGDW
RRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLER
KNERNA-------------------------------EAKRKMALARERKTVKTLGIIMG
TFILCWLPFFIVALVLPF-CESSCH-MPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNA
FKKII-----KCKFCRR-------------------------------------------
------------------------------------------------------------
---------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
HSSRSRDNASANDTSATNMTDDRYWSLT----------VYSHEHLVLTSVILGLFVLCCI
IGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSE
VCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI
-SIPPLF-GWRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMM
IIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKK
KRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEE
ASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITG
AFLICWLPFFIIALIGPF--VDPEG-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSA
FQKIL-----FGKYRRGHR-----------------------------------------
------------------------------------------------------------
---------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
HSSRSRDNASANDTSATNMTDDRYWSLT----------VYSHEHLVLTSVILGLFVLCCI
IGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KVWF--LHSE
VCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMVVWIVALFI
-SIPPLF-GWRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAFYLPMLVMM
IIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKK
KRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEE
ASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRERKAARTLAIITG
AFLICWLPFFIIALIGPF--VDPEG-IPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSA
FQKIL-----FGKYRRGHR-----------------------------------------
------------------------------------------------------------
---------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAEGQEELDWEALYLRLPLQNCSWNSTGWEPNWNVTV---------------------
------------------VPNTTWWQASAPF-----DTPAALVRAAAKAVVLGLLILATV
VGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QRWT--LGPE
LCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIACVWTVSFFV
-CIAQLL-GWKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSFYVPVLIIL
ILYWRIYQTARKRIRRRRGATARGGV--------GPPPVPAGGALVAGGGSGG-------
-----------------------------IAAAVVAVIGRPLPTISETTTTGFTNVSSNN
TSPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLAIITG
AFVACWLPFFVLAILVPT---CDCE-VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHA
FQRLL-----CGRRVRRRRAPQ--------------------------------------
------------------------------------------------------------
---------------
