>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
------------------------------------------------------------
-MNGTE--GDNFYVPFSNKTG--LARSPYEYPQY-YLAEPW---------KYSA-----L
AAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSM
N-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGNF-RFGNTHAIM
GVAFTWIMALAC-AAPPLV-GWS-----RYIPEGMQCSCGPDYYTLNPNFNNESYVVYMF
VVHFLVPFVIIFFCYGRLLCTVKEAAAAQQESA---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
KEVTRMVVLMVIGFLVCWVPYASVAFYIFT--HQGSD-FGATFMTLPAFFAKSSALYNPV
IYILMNKQFRNCMITTL-----CCGKNPLGDDE-SG-ASTSKTEVSSVS-TSPVSPA---
------------------------------------------------------------
-------------------------------
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
------------------------------------------------------------
-MNGTE--GPNFYVPFSNITG--VVRSPFEQPQY-YLAEPW---------QFSM-----L
AAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSL
H-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNF-RFGENHAIM
GVAFTWVMALAC-AAPPLV-GWS-----RYIPEGMQCSCGIDYYTLKPEVNNESFVIYMF
VVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESA---------------------------
------------------------------------------------------------
------------------------------------------------------TTQKAE
KEVTRMVIIMVIFFLICWLPYASVAMYIFT--HQGSN-FGPIFMTLPAFFAKTASIYNPI
IYIMMNKQFRNCMLTSL-----CCGKNPLGDDE-AS-ATASKTETSQVA-PA--------
------------------------------------------------------------
-------------------------------
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
------------------------------------------------------------
-MNGTE--GINFYVPMSNKTG--VVRSPFEYPQY-YLAEPW---------KYRL-----V
CCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAW
N-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGNF-RFSATHAMM
GIAFTWVMAFSC-AAPPLF-GWS-----RYMPEGMQCSCGPDYYTHNPDYHNESYVLYMF
VIHFIIPVVVIFFSYGRLICKVREAAAQQQESA---------------------------
------------------------------------------------------------
------------------------------------------------------TTQKAE
KEVTRMVILMVLGFMLAWTPYAVVAFWIFT--NKGAD-FTATLMAVPAFFSKSSSLYNPI
IYVLMNKQFRNCMITTI-----CCGKNPFGDEDVSSTVSQSKTEVSSVS-SSQVSPA---
------------------------------------------------------------
-------------------------------
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
------------------------------------------------------------
-MNGTE--GKNFYVPMSNRTG--LVRSPFEYPQY-YLAEPW---------QFKI-----L
ALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAI
N-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSSHAFA
GIAFTWVMALAC-AAPPLF-GWS-----RYIPEGMQCSCGPDYYTLNPDYNNESYVIYMF
VCHFILPVAVIFFTYGRLVCTVKAAAAQQQDSA---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
REVTKMVILMVFGFLIAWTPYATVAAWIFF--NKGAD-FSAKFMAIPAFFSKSSALYNPV
IYVLLNKQFRNCMLTTI-----FCGKNPLGDDE-SSTVSTSKTEVSSVS-PA--------
------------------------------------------------------------
-------------------------------
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
------------------------------------------------------------
-MNGTE--GNNFYVPLSNRTG--LVRSPFEYPQY-YLAEPW---------QFKL-----L
AVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAI
N-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGSF-KFSSTHASA
GIAFTWVMAMAC-AAPPLV-GWS-----RYIPEGIQCSCGPDYYTLNPEYNNESYVLYMF
ICHFILPVTIIFFTYGRLVCTVKAAAAQQQDSA---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
REVTKMVILMVLGFLVAWTPYATVAAWIFF--NKGAA-FSAQFMAIPAFFSKTSALYNPV
IYVLLNKQFRSCMLTTL-----FCGKNPLGDEE-SSTVSTSKTEVSSVS-PA--------
------------------------------------------------------------
-------------------------------
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
------------------------------------------------------------
-MKQVPEFHEDFYIPIPLDINNLSAYSPFLVPQD-HLGNQG---------IFMA-----M
SVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFF
N-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGNF-TFKTPHAIA
GCILPWISALAA-SLPPLF-GWS-----RYIPEGLQCSCGPDWYTTNNKYNNESYVMFLF
CFCFAVPFGTIVFCYGQLLITLKLAAKAQADSA---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
REVTKMVVVMVLGFLVCWAPYASFSLWIVS--HRGEE-FDLRMATIPSCLSKASTVYNPV
IYVLMNKQFRSCMM-KM-----VCGKN-IEEDE-AS-TSSQVTQVSSVA-PEK-------
------------------------------------------------------------
-------------------------------
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
------------------------------------------------------------
-MRKMS--EEEFYL-----FKNISSVGPWDGPQY-HIAPVW---------AFYL-----Q
AAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASC
N-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNF-RFSSKHALT
VVLATWTIGIGV-SIPPFF-GWS-----RFIPEGLQCSCGPDWYTVGTKYRSESYTWFLF
IFCFIVPLSLICFSYTQLLRALKAVAAQQQESA---------------------------
------------------------------------------------------------
------------------------------------------------------TTQKAE
REVSRMVVVMVGSFCVCYVPYAAFAMYMVN--NRNHG-LDLRLVTIPSFFSKSACIYNPI
IYCFMNKQFQACIM-KM-----VCGKA-MTDES-DT-CSSQKTEVSTVS-STQVGPN---
------------------------------------------------------------
-------------------------------
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------DLAETVIA-STISIVNQV
S-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIV
GIAFSWIWAAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
KEVTRMVVVMVLAFC---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
-----------------------------------------MAQQWS-LQRLAGRHPQDS
YEDSTQ--SSIFTYTNSN-----STRGPFEGPNY-HIAPRW---------VYHL-----T
SVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQV
Y-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNV-RFDAKLAIV
GIAFSWIWAAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
KEVTRMVVVMVLAFCFCWGPYAFFACFAAA--NPGYP-FHPLMAALPAFFAKSATIYNPV
IYVFMNRQFRNCILQLF----------GKKVDDGSELSSASKTEVSSV---SSVSPA---
------------------------------------------------------------
-------------------------------
>    10== Z68193   1 human Red Opsin <>[]
-----------------------------------------MAQQWS-LQRLAGRHPQDS
YEDSTQ--SSIFTYTNSN-----STRGPFEGPNY-HIAPRW---------VYHL-----T
SVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQV
S-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV-RFDAKLAIV
GIAFSWIWSAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLM
VTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESE---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
KEVTRMVVVMIFAYCVCWGPYTFFACFAAA--NPGYA-FHPLMAALPAYFAKSATIYNPV
IYVFMNRQFRNCILQLF----------GKKVDDGSELSSASKTEVSSV---SSVSPA---
------------------------------------------------------------
-------------------------------
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
-----------------------------------------MTEAWNVAVFAARRSRDD-
-DDTTR--GSVFTYTNTN-----NTRGPFEGPNY-HIAPRW---------VYNL-----V
SFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQI
F-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNI-KFDSKLAII
GIVFSWVWAWGW-SAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSVELGCQSFMLTLM
ITCCFLPLFIIIVCYLQVWMAIRAVAAQQKESE---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
REVSRMVVVMIVAFCICWGPYASFVSFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPV
IYVFMNRQFRNCIMQLF----------GKKVDDGSEASTTSRTEVSSVS-NSSVAPA---
------------------------------------------------------------
-------------------------------
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
------------------------------------------MAAWE-AAFAARRRHEE-
-EDTTR--DSVFTYTNSN-----NTRGPFEGPNY-HIAPRW---------VYNL-----T
SVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQI
S-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGNI-KFDGKLAVA
GILFSWLWSCAW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLM
VTCCFFPLAIIILCYLQVWLAIRAVAAQQKESE---------------------------
------------------------------------------------------------
------------------------------------------------------STQKAE
KEVSRMVVVMIVAYCFCWGPYTFFACFAAA--NPGYA-FHPLAAALPAYFAKSATIYNPI
IYVFMNRQFRNCILQLF----------GKKVDDGSEVST-SRTEVSSVS-NSSVSPA---
------------------------------------------------------------
-------------------------------
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
------------------------------------------------------------
-----M--SSNSSQAPPN-----GTPGPFDGPQWPYQAPQS---------TYVG-----V
AVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNI
N-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGDF-QFQRRHAVS
GCAFTWGWALLW-SAPPLL-GWS-----SYVPEGLRTSCGPNWYTGGSN--NNSYILSLF
VTCFVLPLSLILFSYTNLLLTLRAAAAQQKEAD---------------------------
------------------------------------------------------------
------------------------------------------------------TTQRAE
REVTRMVIVMVMAFLLCWLPYSTFALVVAT--HKGII-IQPVLASLPSYFSKTATVYNPI
IYVFMNKQFQSCLLEML-----CCGYQPQRTGKASPGTPGPHADVTAAGLRNKVMPAHPV
------------------------------------------------------------
-------------------------------
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
--------------------------------------------MESGNVSSSLFGNVST
ALRPEARLSA---E-----TRLLGWNVPPEELR--HIPEHWLTYPEPPESMNYL-----L
GTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSF
H-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIA
MIIFIYMYATPW-VVACYTETWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIF
FFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLR------------------
------------------------------------------------------------
-------------------------------------------------SNVDKNKETAE
IRIAKAAITICFLFFCSWTPYGVMSLIGAF--GDKTL-LTPGATMIPACACKMVACIDPF
VYAISHPRYRMELQKRCPWL--ALNEKAPESSA----VASTST-TQEPQQTTAA------
------------------------------------------------------------
-------------------------------
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
--------------------------------------------MEYHNVSSVL-GNVSS
VLRPDARLSA---E-----SRLLGWNVPPDELR--HIPEHWLIYPEPPESMNYL-----L
GTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSF
H-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIA
MIIFIYLYATPW-VVACYTESWG-----RFVPEGYLTSCTFDYLTDN--FDTRLFVACIF
FFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVDSLR------------------
------------------------------------------------------------
-------------------------------------------------SNVDKSKEAAE
IRIAKAAITICFLFFASWTPYGVMSLIGAF--GDKTL-LTPGATMIPACTCKMVACIDPF
VYAISHPRYRMELQKRCPWL--AISEKAPESRA----AISTST-TQEQQQTTAA------
------------------------------------------------------------
-------------------------------
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
--------------------------------------------------MEPLCNASEP
PLRPEAR-SSGNGD-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPASMHYM-----L
GVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSF
H-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVI
MNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIF
FFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLR------------------
------------------------------------------------------------
-------------------------------------------------SNVDKSKETAE
IRIAKAAITICFLFFVSWTPYGVMSLIGAF--GDKSL-LTQGATMIPACTCKLVACIDPF
VYAISHPRYRLELQKRCPWL--GVNEKSGEISS----AQSTTT-QEQQQTTAA-------
------------------------------------------------------------
-------------------------------
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
--------------------------------------------------MDALCNASEP
PLRPEARMSSGSDE-----LQFLGWNVPPDQIQ--YIPEHWLTQLEPPASMHYM-----L
GVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSF
H-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVI
MNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDN--FDTRLFVGTIF
LFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMNVESLR------------------
------------------------------------------------------------
-------------------------------------------------SNVDKSKETAE
IRIAKAAITICFLFFVSWTPYGVMSLIGAF--GDKSL-LTPGATMIPACTCKLVACIEPF
VYAISHPRYRMELQKRCPWL--GVNEKSGEASS----AQSTTT-QEQTQQTSAA------
------------------------------------------------------------
-------------------------------
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
-----------------------------------------------------MTNATGP
QMAYYGAASMDFGYPE---GVSIVDFVRPEIKP--YVHQHWYNYPPVNPMWHYL-----L
GVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCF
SGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNGP-KLTTGKAVV
FALISWVIAIGC-ALPPFF-GWG-----NYILEGILDSCSYDYLTQD--FNTFSYNIFIF
VFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMNVSTLR------------------
------------------------------------------------------------
-------------------------------------------------S-NEADAQRAE
IRIAKTALVNVSLWFICWTPYALISLKGVM--GDTSG-ITPLVSTLPALLAKSCSCYNPF
VYAISHPKYRLAITQHLPWF--CVHETETKSND----DSQSNS-TVAQDKA---------
------------------------------------------------------------
-------------------------------
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
-----------------------------------------------------MANVTGP
QMAFYGSGAATFGYPE---GMTVADFVPDRVKH--MVLDHWYNYPPVNPMWHYL-----L
GVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCF
SGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNGP-KLTQGKATF
MCGLAWVISVGW-SLPPFF-GWG-----SYTLEGILDSCSYDYFTRD--MNTITYNICIF
IFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTNLR------------------
------------------------------------------------------------
-------------------------------------------------S-NEAETQRAE
IRIAKTALVNVSLWFICWTPYAAITIQGLL--GNAEG-ITPLLTTLPALLAKSCSCYNPF
VYAISHPKFRLAITQHLPWF--CVHEKDPNDVE----ENQSSN-TQTQEKS---------
------------------------------------------------------------
-------------------------------
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-----------------------------------------------MESFAVAAAQLGP
HFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPIWAKI-----L
TAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALG
KM---------------------------YVPEGNLTSCGIDYLERD--WNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------
------------------------------------------------------------
-------------------------------------------------S-SEDAEKSAE
GKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPI
VYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----DAQSQA-TASEAESKA-------
------------------------------------------------------------
-------------------------------
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-----------------------------------------------MESFAVAAAQLGP
HFA-----PLS--------NGSVVDKVTPDMAH--LISPYWNQFPAMDPIWAKI-----L
TAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALG
KIAYIWFMSSIW-CLAPAF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------
------------------------------------------------------------
-------------------------------------------------S-SEDAEKSAE
GKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPI
VYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----DAQSQA-TASEAESKA-------
------------------------------------------------------------
-------------------------------
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-----------------------------------------------MDSFAAVATQLGP
QFA-----APS--------NGSVVDKVTPDMAH--LISPYWDQFPAMDPIWAKI-----L
TAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLY
F-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGR-PMTIPLALG
KIAYIWFMSTIWCCLAPVF-GWS-----RYVPEGNLTSCGIDYLERD--WNPRSYLIFYS
IFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR------------------
------------------------------------------------------------
-------------------------------------------------S-SEDADKSAE
GKLAKVALVTISLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGACFAKSAACYNPI
VYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----EAQSQA-TTSEAESKA-------
------------------------------------------------------------
-------------------------------
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
------------------------------------------MERSHLPETPFDLAHSGP
RFQ-----AQSSG------NGSVLDNVLPDMAH--LVNPYWSRFAPMDPMMSKI-----L
GLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFY
Y-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIM
KILFIWMMAVFW-TVMPLI-GWS-----AYVPEGNLTACSIDYMTRM--WNPRSYLITYS
LFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLR------------------
------------------------------------------------------------
-------------------------------------------------S-SEDCDKSAE
GKLAKVALTTISLWFMAWTPYLVICYFGLF--KI-DG-LTPLTTIWGATFAKTSAVYNPI
VYGISHPKYRIVLKEKCPMC--VFGNTDEPKPD----APASDTETTSEADSKA-------
------------------------------------------------------------
-------------------------------
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
------------------------------------------MERSLLPEPPLAMALLGP
RFE-----AQTGG------NRSVLDNVLPDMAP--LVNPHWSRFAPMDPTMSKI-----L
GLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFY
Y-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGINGT-PMTIKTSIM
KIAFIWMMAVFW-TIMPLI-GWS-----SYVPEGNLTACSIDYMTRQ--WNPRSYLITYS
LFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMNVKSLR------------------
------------------------------------------------------------
-------------------------------------------------S-SEDCDKSAE
NKLAKVALTTISLWFMAWTPYLIICYFGLF--KI-DG-LTPLTTIWGATFAKTSAVYNPI
VYGISHPNDRLVLKEKCPMC--VCGTTDEPKPD----APPSDTETTSEAESKD-------
------------------------------------------------------------
-------------------------------
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
-----------------------------------------------------MIAVSGP
SYE-----AFSYGGQARFNNQTVVDKVPPDMLH--LIDANWYQYPPLNPMWHGI-----L
GFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCY
Y-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSGK-PLSINGALI
RIIAIWLFSLGW-TIAPMF-GWN-----RYVPEGNMTACGTDYFNRG--LLSASYLVCYG
IWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMNVASLR------------------
------------------------------------------------------------
-------------------------------------------------S-SENQNTSAE
CKLAKVALMTISLWFMAWTPYLVINFSGIF--NL-VK-ISPLFTIWGSLFAKANAVYNPI
VYGISHPKYRAALFAKFPSL--AC-AAEPSSDA----VSTTSG-TTTVTDNEKSNA----
------------------------------------------------------------
-------------------------------
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
-------------------------------------------------------MANQL
SYS-----SLGWPYQP---NASVVDTMPKEMLY--MIHEHWYAFPPMNPLWYSI-----L
GVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCF
A-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAA-PLTHKKATL
LLLFVWIWSGGW-TILPFF-GWS-----RYVPEGNLTSCTVDYLTKD--WSSASYVVIYG
LAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLR------------------
------------------------------------------------------------
-------------------------------------------------ANADQQKQSAE
CRLAKVAMMTVGLWFMAWTPYLIISWAGVF--SSGTR-LTPLATIWGSVFAKANSCYNPI
VYGISHPRYKAALYQRFPSL--ACGSGESGSDV----KSEASA-TTTMEEKPKIPEA---
------------------------------------------------------------
-------------------------------
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
------------------------------------------------------------
MVESTTLVNQTWWY-----NPTV------------DIHPHWAKFDPIPDAVYYS-----V
GIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAF
M-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFL
MIIFVWMWSIVW-SVGPVF-NWG-----AYVPEGILTSCSFDYLSTD--PSTRSFILCMY
FCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELR------------------
------------------------------------------------------------
-------------------------------------------------K-AQ-AGASAE
MKLAKISMVIITQFMLSWSPYAIIALLAQF--GPAEW-VTPYAAELPVLFAKASAIHNPI
VYSVSHPKFREAIQTTFPWLLTCCQFDEKECED----ANDAEE-EVVASER--GGESRDA
AQMKEMMAMMQKMQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYP
PQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
------------------------------------------------------------
-MGRDLRDNETWWY-----NPSI------------VVHPHWREFDQVPDAVYYS-----L
GIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCF
L-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFI
MIIFVWLWSVLW-AIGPIF-GWG-----AYTLEGVLCNCSFDYISRD--STTRSNILCMF
ILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELR------------------
------------------------------------------------------------
-------------------------------------------------K-AQ-AGANAE
MRLAKISIVIVSQFLLSWSPYAVVALLAQF--GPLEW-VTPYAAQLPVMFAKASAIHNPM
IYSVSHPKFREAISQTFPWVLTCCQFDDKETED----DKDAET-EIPAGESSDAAPSADA
AQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYPPQGYPP---P
PQGAPPQGAPP------AAPPQGVDNQAYQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
---------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS-
--EVTASPAPTWDAPPDNA------SGCGE-------------QINYGRVEKVV-----I
GSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVEPDSVIALN
G----------------------------------------------------IVKLQKE
------------------VEECAN------------------LSRLLKHERKNISIFKRE
QKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPF
IYAFFNRDLRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADY
CRKKGHDS----------------------------------------------------
-------------------------------
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
-----------------------------------------------------MPHLLSG
FLEVTASPAPTWDAPPDNV------SGCGE-------------QINYGRVEKVV-----I
GSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLN
G----------------------------------------------------VVKLQKE
------------------VEECAN------------------LSRLLKHERKNISIFKRE
QKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPF
IYAFFNRDLRPTSRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDH
CGKKGHDT----------------------------------------------------
-------------------------------
>    31=p A47425 serotonin receptor 5HT-7 - rat
-----------------------------------------------------MPHLLSG
FLEVTASPAPTWDAPPDNV------SGCGE-------------QINYGRVEKVV-----I
GSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDL
IGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK
MILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF----------GYTIYST
AVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFPRVQPESVISLN
G----------------------------------------------------VVKLQKE
------------------VEECAN------------------LSRLLKHERKNISIFKRE
QKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPF
IYAFFNRDLRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDH
CGKKGHDT----------------------------------------------------
-------------------------------
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
----------MDVLSPG-------------------------------------------
--------------QGNNT------TSPPAPF---ETGGNTTGISDVTVSYQVI-----T
SLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQV
L-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAA
LISLTWLIGFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH----------GYTIYST
FGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKK-----SVN
G--ESGSRNWRLGVESKAGGALCANGAVRQGDDGAAL--EVIEVHRVGNSKEHLPLPSEA
GPTPCAPAS------------------FERKNERNA-------------EAKRKMALARE
RKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINWLGYSNSLLNPV
IYAYFNKDFQNAFKKII-----KCKFCRQ-------------------------------
------------------------------------------------------------
-------------------------------
>    33=p A35181 serotonin receptor class 1A - rat
----------MDVFSFG-------------------------------------------
--------------QGNNT------TASQEPF---GTGGNVTSISDVTFSYQVI-----T
SLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQV
L-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAA
LISLTWLIGFLI-SIPPML-GWRTPEDRSDPD---ACTISKDH----------GYTIYST
FGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKK-----SLN
G--QPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATL--EVIEVHRVGNSKEHLPLPSES
GSNSYAPAC------------------LERKNERNA-------------EAKRKMALARE
RKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPALLGAIINWLGYSNSLLNPV
IYAYFNKDFQNAFKKII-----KCKFCRR-------------------------------
------------------------------------------------------------
-------------------------------
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPS----GLRSTGLTTPGLSPTGLVTSDFND-SYGLTGQ
FINGSHSSRSRDNASANDT------SATNM------TDDRYWSLTVYSHEHLVL-----T
SVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEI
S-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILL
MIMVVWIVALFI-SIPPLF-GWRDPNN--DPDKTGTCIISQDK----------GYTIFST
VGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCN
GCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIE
TAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRE
RKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPI
IYTIFSPEFRSAFQKIL-----FGKYRRGHR-----------------------------
------------------------------------------------------------
-------------------------------
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPS----GLRSTGLTTPGLSPTGLVTSDFND-SYGLTGQ
FINGSHSSRSRDNASANDT------SATNM------TDDRYWSLTVYSHEHLVL-----T
SVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEI
S-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILL
MIMVVWIVALFI-SIPPLF-GWRDPNN--DPDKTGTCIISQDK----------GYTIFST
VGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCN
GCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIE
TAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-------------RTREKLELKRE
RKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFARSFVLWLGYFNSLLNPI
IYTIFSPEFRSAFQKIL-----FGKYRRGHR-----------------------------
------------------------------------------------------------
-------------------------------
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
-MEGAEGQEELDWEAL--------------------------------------------
-----YLRLPLQNCSWNSTGWEPNWNVTVV------PNTTWWQASAPFDTPAALVRAAAK
AVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEV
V-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGM
MIACVWTVSFFV-CIAQLL-GWKDPDWNQRVSEDLRCVVSQDV----------GYQIFAT
ASSFYVPVLIILILYWRIYQTARKRIRR------RRGATARGGVGPPPVPAG--------
-------------------------GALVAGGGSGGIAAAVVAV-----IGRPLPTISET
TTTGFTNVSSNNTSPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRE
RKAAKTLAIITGAFVACWLPFFVLAILVPT-CD--CE-VSPVLTSLSLWLGYFNSTLNPV
IYTVFSPEFRHAFQRLL-----CGRRVRRRRAPQ--------------------------
------------------------------------------------------------
-------------------------------
